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More than 325 papers have been published. Here are the recently selected publications:

  • Genxi Li, “Nano-inspired biosensors for protein assay with clinical applications”, Elsevier, Cambridge, United States, 2018

  • Chao Li, Xiaolu Hu, Jianyang Lu, Xiaoxia Mao, Yang Xiang, Yongqian Shu, Genxi Li. Design of DNA nanostructure-based interfacial probes for the electrochemical detection of nucleic acids directly in whole blood. Chem. Sci., 2018, 9: 979-984

  • Xiaoxia Mao, Guifang Chen, Zihan Wang, Yuanguang Zhang, Xiaoli Zhu, Genxi Li. Surface-immobilized and self-shaped DNA hydrogels and their application in Biosensing. Chem. Sci., 2018, 9: 811-818

  • Tao Gao, Chaoli Mu, Hai Shi, Liu Shi, Xiaoxia Mao, Genxi Li. Embedding capture-magneto-catalytic activity into a nanocatalyst for the determination of lipid kinase. ACS Appl. Mater. Interfaces 2018, 10: 59-65

  • Jing Zhao, Huinan Chen, Yingying Tang, Hong Chen, Guifang Chen, Yongmei Yin, Genxi Li. Research progresses on the functional polypeptides in the detection and imaging of breast cancer. J. Mater. Chem. B, 2018, 6: 2510-2523

  • Xiaoxia Chen, Jing Zhao, Tianshu Chen, Tao Gao, Xiaoli Zhu, Genxi Li. Nondestructive analysis of tumor-associated membrane protein integrating imaging and amplified detection in situ based on dual-labeled DNAzyme. Theranostics, 2018, 8: 1075-1083

  • Chang Feng, Zihan Wang, Tianshu Chen, Xiaoxia Chen, Dongsheng Mao, Jing Zhao, Genxi Li, A dual-enzyme-assisted three-dimensional DNA walking machine using T4 polynucleotide kinase as activators and application in polynucleotide kinase assays. Anal. Chem., 2018, 90, 2810−2815

  • Juan Zhang, Defeng Li, Xiquan Yue, Meiling Zhang, Ping Liu, Genxi Li, Colorimetric in situ assay of membrane-bound enzyme based on lipid bilayer inhibition of ion transport. Theranostics, 2018, 8: 3275-3283

  • Shuai Wu, Chao Li, Hai Shi, Yue Huang, Genxi Li, Design of metal-organic frameworks-based nanoprobes for multicolor detection of DNA targets with improved sensitivity. Anal. Chem., 2018, 90: 9929-9935

  • Liu Shi, Chaoli Mu, Tao Gao, Tianshu Chen, Shuang Hei, Jie Yang, Genxi Li, DNA nanoflower blooms in nanochannel: a new strategy for miRNA detection. Chem Commun., 2018, 54: 11391-11394

  • Chao  Li, Jiehua Ma, Hai Shi, Xiaolu Hu, Yang Xiang, Yuanyang Li, Genxi Li, Design of a stretchable DNAzyme for sensitive and multiplexed detection of antibodies. Anal. Chim. Acta., 2018, 1041: 102-107

  • Chao Li, Jianyang Lu, Xiaolu Hu, Chang Feng, Yang Xiang, Yannis Karamanos, Genxi Li. Assembly of nanoconjugates as new kind inhibitor of the aggregation of amyloid peptides associated with Alzheimer’s disease. Part. Part. Syst. Charact., 2018, 35: 1700384

  • Hai Shi, Tao Gao, Liu Shi, Tianshu Chen, Yang Xiang, Yuanyang Li, Genxi Li, Molecular imaging of telomerase and the enzyme activity triggered drug release by using a conformation-switchable nanoprobe in cancerous cells, Sci. Rep., 2018, 8: 16341

  • Jin Jiao, Tao Gao, Hai Shi, Anzhi Sheng, Yang Xiang, Yongqian Shu, Genxi Li, A method to directly assay circRNA in real samples, Chem. Commun., 2018, 54: 13451-13454

  • Jinlong Li, Guangwu He, Bei Wang, Liu Shi, Tao Gao, Genxi Li, Fabrication of reusable electrochemical biosensor and its application for the assay of α-glucosidase activity, Anal. Chim. Acta, 2018, 1026: 140-146

  • Yi Yang, Chao Li, Hai Shi, Tianshu Chen, Zhaoxia Wang, Genxi Li, A pH-responsive bioassay for paper-based diagnosis of exosomes via mussel inspired surface chemistry, Talanta, online available

  • Tao Gao, Lingling Li, Tianshu Chen, Liu Shi, Yang Yang, Genxi Li, DNA-Oriented Shaping of Cell Features for the Detection of Rare Disseminated Tumor Cells, Anal. Chem., Online available

  • Juan Zhang, Hong Chen, Ya Cao, Chang Feng, Xiaoli Zhu, Genxi Li, Design of a nanoprobe based on its binding with amino acid residues on cell surface and its application to electrochemical analysis of cells, Anal. Chem., Online available

  • Chang Feng, Xiaoxia Mao, Hai Shi, Bing Bo, Xiaoxia Chen, Tianshu Chen, Xiaoli Zhu, Genxi Li. Detection of microRNA: a point-of-care testing method based on a pH-responsive and highly efficient isothermal amplification. Anal. Chem., 2017, 89: 6631-6636

  • Chao Li, Liu Shi, Yaqin Tao, Xiaoxia Mao, Yang Xiang, Genxi Li. Flexible regulation of DNA displacement reaction through nucleic acid-recognition enzyme and its application in keypad lock system and biosensing. Sci. Rep., 2017, 7: 10017

  • Tao Gao, Bei Wang, Liu Shi, Xiaoli Zhu, Yang Xiang, Jun-ichi Anzai, Genxi Li. Ultrasensitive quantitation of plasma membrane proteins via isRTA. Anal. Chem., 2017, 89: 10776-10782

  • Jiehua Ma, Xiaolu Hu, Yaqin Tao, Chao Li, Xiaoxia Mao, Genxi Li. Gold nanoparticle-based biosensors for the assay of tumor marker proteins with clinical applications. Advanced Materials Letters, 2017, 8(12), 1125-1131

  • Xiaonan Wang, Ying Liu, Juan Zhang, Genxi Li. Oxime chemistry-mediated covalent capturing on electrode surface with guanidinium recognition and application for aldolase activity assay. Sensors and Actuators B, 2017, 242: 687-693

  • Xiaoli Zhu, Xiaoxia Mao, Zihan Wang, Chang Feng, Guifang Chen, Genxi Li. Fabrication of nanozyme@DNA hydrogel and its application in biomedical analysis. Nano Research, 2017, 10: 959-970

  • Xiaoli Zhu, Xiaoxia Chen, Fangfang Ban, Ya Cao, Jing Zhao, Guifang Chen, Genxi Li. The design of a mechanical wave-like DNA nanomachine for the fabrication of a programmable and multifunctional molecular device. Chem. Commun., 2017, 53: 10504-10507

  • Tao Gao, Shiyu Gu, Chaoli Mu, Meiling Zhang, Jie Yang, Ping Liu, Genxi Li. Electrochemical assay of lipid kinase activity facilitated by liposomes. Electrochimica Acta, 2017, 252: 362-367

  • Chao Li, Yaqin Tao, Yi Yang, Yang Xiang, Genxi Li. In vitro analysis of DNA-protein interactions in gene transcription using DNAzyme-based electrochemical assay. Anal. Chem., 2017, 89: 5003-5007

  • Jinlong Li, Tao Gao, Shiy Gu, Jun Zhi, Jie Yang, Genxi Li. An electrochemical biosensor for the assay of alpha-fetoprotein-L3 with practical applications. Biosensors and Bioelectronics, 2017, 87: 352-357

  • Xiaolu Hu, Chao Li, Chang Feng, Xiaoxia Mao, Yang Xiang, Genxi Li. One-Step colorimetric detection of antibody based on protein-induced unfolding of G-quadruplex switch. Chem. Commun., 2017, 53: 4692-4694

  • Xiaoli Zhu, Yaoyao Chen, Chang Feng, Wei Wang, Bing Bo, Ruixin Ren, Genxi Li. Assembly of self-cleaning electrode surface for the development of refreshable biosensors, Anal. Chem. , 2017, 89: 4131-4138

  • Chang Feng, Bing Bo, Xiaoxia Mao, Hai Shi, Xiaoli Zhu*, Genxi Li. From interface to solution: integrating immunoassay with netlike rolling circle amplification for ultrasensitive detection of tumor biomarker. Theranostics, 2017, 7: 31-39

  • Chao Li, Yaqin Tao, Yi Yang, Chang Feng, Yang Xiang, Genxi Li. Dynamic sandwich-type electrochemical assay for protein quantification and protein-protein interaction. Analyst, 2017, 142: 4399-4404

  • Juan Zhang, Xiaonan Wang, Tingjun Chen, Chang Feng, Genxi Li. Electrochemical analysis of enzyme based on the self-assembly of lipid bilayer on an electrode surface mediated by hydrazone chemistry. Anal. Chem., 2017, 89: 13245-13251





  • Tao Gao, Liudi Li, Bei Wang, Jun Zhi, Yang Xiang, Genxi Li. Dynamic electrochemical control of cell capture−and−release based on redox-controlled host−guest interactions.
    Anal. Chem., 2016, 88: 9996-10001

  • Yue Huang, Hao Li, Qiongxuan Fan, Lei Wang, Yao Wang, Genxi Li. Multifunctional nanocatalyst-based ultrasensitive detection of human tissue transglutaminase 2.
    Biosensors and Bioelectronics, 2016, 83: 85-90

  • Weiwei Li, Hao Li, Shuai Wu, Chang Feng, Genxi Li. Highly sensitive protein detection based on DNAzyme cycling activated surface assembly of peptide decorated nanoparticles. Electrochem. Comm., 2016, 71: 84-88

  • Qiongxuan Fan, Chao Li, Yaqin Tao, Xiaoxia Mao, Genxi Li. Simple and fast screening of G-quadruplex ligands with electrochemical detection system. Talanta, 2016, 160: 144-147

  • Dan Wu, Chao Li, Xiaolu Hu, Xiaoxia Mao, Genxi Li. Electrochemical detection of DNA 3’-phosphatases based on surface-extended DNA nanotail strategy.
    Anal. Chim. Acta,
    2016, 924: 29-34

  • Dan Wu, Tao Gao, Lin Lei, Dawei Yang, Xiaoxia Mao, Genxi Li. Colorimetric detection of proteins based on target-induced activation of aptazyme.
    Anal. Chim. Acta,
    2016, 942: 68-73

  • Hao Li, Yue Huang, Yue Yu, Yao Wang, Genxi Li. Recognition-induced covalent capturing and labeling as a general strategy for protein detection.
    Biosensors and Bioelectronics,
    2016, 80: 560-565

  • Hao Li, Yue Huang, Yue Yu, Genxi Li, Yannis Karamanos. Self-catalyzed assembly of peptide scaffolded nanozyme as a dynamic biosensing system.
    ACS Appl. Mater. Interfaces
    , 2016, 8: 2833-2839

  • Hao Li, Weiwei Li, Fengzhen Liu, Zhaoxia Wang, Genxi Li, Yannis Karamanos. Detection of tumor invasive biomarker using a peptamer of signal conversion and signal amplification.
    Anal. Chem.
    , 2016, 88: 3662-3668

  • Hao Li, Yue Huang, Yue Yu, Tianqi Li, Genxi Li, Jun-ichi Anzai. Enzymatically regulated peptide pairing and catalysis for the bioanalysis of extracellular prometastatic activities of functionally linked enzymes. Sci. Rep., 2016, 6: 25362

  • Tao Gao, Shiyu Gu, Fenzheng Liu, Liudi Li, Zhaoxia Wang, Jie Yang, Genxi Li. Investigation of MTH1 activity via mismatch-based DNA chain elongation.
    Anal. Chim. Acta,
    905: 66-71

  • Chao Li, Yucai Yang, Dan Wu, Tianqi Li, Yongmei Yin, Genxi Li. Improvement of enzyme-linked immunosorbent assay for the multicolor detection of biomarkers.
    Chem. Sci.
    , 2016, 7: 3011-3016

  • Chao Li, Jiehua Ma, Qiongxuan Fan, Yaqin Tao, Genxi Li. Dynamic light scattering (DLS)-based immunoassay for ultra-sensitive detection of tumor marker protein.
    Chem. Comm.
    , 2016, 52: 7850-7853

  • Luming Wei, Xiaoying Wang, Dan Wu, Chao Li, Yongmei Yin, Genxi Li. Proximity ligation-induced assembly of DNAzymes for simple and cost-effective colorimetric detection of proteins with high sensitivity. Chem. Comm., 2016, 52: 5633-5636

  • Jiehua Ma, Chao Li, Yaqin Tao, Chang Feng, Genxi Li. Electrochemical detection of
    Nanog in cell extracts via target-induced resolution of an electrode-bound DNA pseudoknot. Biosensors and Bioelectronics, 2016, 86: 933-938

  • Chao Li, Dan Wu, Xiaolu Hu, Yang Xiang, Yongqian Shu, Genxi Li. One-Step modification of electrode surface for ultrasensitive and highly selective detection of nucleic acids with practical applications. Anal. Chem., 2016, 88: 7583-7590

  • Xiaoli Zhu, Siyu Liu, Jiepei Cao, Xiaoxia Mao, Genxi Li. Switchable DNA wire: deposition-stripping of copper nanoclusters as an “ON-OFF” nanoswitch. Sci. Rep., 2016, 6: 19515

  • Yue Yu, Hao Li, Luming Wei, Liudi Li, Yitao Ding, Genxi Li. Electrochemical detection and distribution analysis of β-catenin for the evaluation.of invasion and metastasis in hepatocellular carcinoma. Anal. Chem., 2016, 88: 3879-3884

  • Yuanyuan Zhang, Hao Li, Yue Huang, Lizhou Sun, Genxi Li. Peptide-Induced bio-mineralization as a bio-mimetic means of detecting proteins in a mineralizing bio-context.
    Nano Res.,
    2016, 9: 1489-1496

  • Juan Zhang, Yangyang Chen, Defeng Li, Ya Cao, Zhaoxia Wang, Genxi Li.
    Colorimetric determination of islet amyloid polypeptide fibrils and their inhibitors using resveratrol functionalized gold nanoparticles. Microchim Acta, 2016, 183: 659-665 

  • Yue Huang, Hao Li, Lei Wang, Xiaoxia Mao, Genxi Li. Highly sensitive protein detection based on smart hybrid nanocomposite-controlled switch of DNA polymerase activity.
    ACS Appl. Mater. Interfaces, 2016, 8: 28202-28207

  • Chang Feng, Xiaoxia Mao, Yucai Yang, Xiaoli Zhu, Yongmei Yin, Genxi Li. Rolling circle amplification in electrochemical biosensor with biomedical applications (review)
    J. Electroanal. Chem., 2016, 781: 223-232

  • Yue Yu, Hao Li, Yucai Yang, Yitao Ding, Zhaoxia Wang, Genxi Li. Evaluating tumor-associated activity of extracellular sulfatase by analyzing naturally occurring substrate in tumor microenvironment of hepatocellular carcinoma, Anal. Chem., 2016, 88: 12287-12293

  • Xiaoli Zhu, Chang Feng, and Genxi Li, “Nicking Enzyme-Assisted Branched-Chain RCA Reaction for Cascade DNA Amplification”, in “Rolling Circle Amplification (RCA) Toward New Clinical Diagnostics and Therapeutics”, Edited by Vadim V. Demidov, pp. 49-56, Springer, Switzerland, 2016


  • Chao Li, Yucai Yang, Luming Wei, Xiaoying Wang, Zhaoxia Wang, Yongmei Yin, Genxi Li.
    An array-based approach to determine different subtype and differentiation of non-small cell lung cancer. Theranostics,2015, 5: 6270


  • Limin Ning, Dawei Yang, Tao Gao, Shan Lu, Yongmei Yin, Genxi Li. A new method to evaluate trinucleotide repeats length polymorphism. Talanta,2015, 143: 414418


  • Luming Wei, Xiaoying Wang, Chao Li, Xiaoxi Li, Yongmei Yin, Genxi Li. Colorimetric assay for protein detection based on “nano-pumpkin” induced aggregation of peptide-decorated gold nanoparticles. Biosensors and Bioelectronics, 2015, 71: 348352


  • Tao Gao, Fengzhen Liu, Dawei Yang, Yue Yu, Zhaoxia Wang, Genxi Li. Assembly of selective biomimetic surface on an electrode surface: a design of nano-bio interface for biosensing. Anal. Chem., 2015, 87: 56835689


  • Chao Li, Xiaoxi Li, Luming Wei, Muyun Liu, Yangyang Chen, Genxi Li. Simple electrochemical sensing of attomolar protein using fabricated complexes with enhanced surface binding avidity. Chem. Sci., 2015, 6: 43114317


  • Yue Huang, Hao Li, Yuanyuan Zhang, Weiwei Li, Lizhou Sun, Genxi Li. Ultrasensitive and feasibly achieved protein detection based on the integration of three signal amplification reactions via sharing a DNA sequence. Chem. Comm., 2015, 51: 1100411007 (cover paper)


  • Dawei Yang, Liming Ning, Tao Gao, Zonghuang Ye, Genxi Li. Enzyme-free dual amplification strategy for protein assay by coupling toehold-mediated DNA strand displacement reaction with hybridization chain reaction. Electrochem. Commun., 2015, 58: 3336


  • Juan Zhang, Ying Liu, Jun Lv, Ya Cao, Genxi Li. Dipeptidyl peptidase-IV activity assay and inhibitor screening using a gold nanoparticle-modified gold electrode with an immobilized enzyme substrate. Microchim. Acta, 2015, 182: 281288


  • Juan Zhang, Ying Liu, Jun Lv, Genxi Li. A colorimetric method for α-glucosidase activity assay and its inhibitor screening based on aggregation of gold nanoparticles induced by specific recognition between phenylenediboronic acid and 4-aminophenyl-α-Dglucopyranoside. Nano Res., 2015, 8: 920930


  • Xiaoli Zhu, Bin Zhang, Zonghuang Ye, Hai Shi, Yalan Shen, Genxi Li. An ATP-responsive smart gate fabricated with a graphene oxide-aptamer-nanochannel architecture. Chem. Comm., 2015, 51: 640643 (inside front cover paper)


  • Xiaoli Zhu, Chang Feng, Bin Zhang, Hui Tong, Tao Gao, Genxi Li. A netlike rolling circle nucleic acid amplification technique. Analyst, 2015, 140: 7478


  • Jing Zhao, Suisui Hu, Ya Cao, Bin Zhang, Genxi Li. Electrochemical detection of protein based on hybridization chain reaction-assisted formation of copper nanoparticles. Biosensors and Bioelectronics, 2015, 66: 327331


  • Yangyang Chen, Ying Liu, Chen Chen, Jun Lv, Juan Zhang, Genxi Li. An electrochemical method to assay the activity of NAD(P)H : quinone oxidoreductase 1. Sensors and Actuators B, 2015, 216: 343348


  • Xiaoli Zhu, Yalan Shen, Jiepei Cao, Li Yin, Fangfang Ban, Yongqian Shu, Genxi Li. Detection of microRNA SNPs with ultrahigh specificity by using reduced graphene oxide-assisted rolling circle amplification. Chem. Comm., 2015, 51: 1000210005


  • Juan Zhang, Jun Lv, Xiaonan Wang, Defeng Li, Zhaoxia Wang, Genxi Li. A simple and visible colorimetric method through Zr4+-phosphate coordination for the assay of protein tyrosine phosphatase 1B and its inhibitor screening. Analyst, 2015, 140: 57165723


  • Fengzhen Liu, Tao Gao, Zonghuang Ye, Dawei Yang, Zhaoxia Wang, Genxi Li. An electrochemical method to assay human 8-oxoguanine DNA glycosylase 1. Electrochem. Commun., 2015, 50: 5154


  • Yuanyuan Zhang, Hao Li, Yue Huang, Tingting Yin, Lizhou Sun, Genxi Li. Sensitive detection of a serum biomarker based on peptide nucleic acid-coupled dual cycling reactions. Anal. Chim. Acta, 2015, 882: 2731


  • Yue Yu, Hao Li, Bin Zhang, Xiaoshu Pan, Xiaoli Zhu, Yitao Ding, Genxi Li. Peptide network for detection of tissue-remodeling enzyme in the prognosis of hepatocellular carcinoma. ACS Appl. Mater. Interfaces, 2015, 7: 44014405


  • Hao Li, Yue Huang, Yue Yu, Weiwei Li, Yongmei Yin, Genxi Li. Peptide-based method for detection of metastatic transformation in primary tumors of breast cancer. Anal. Chem., 2015, 87: 92519256


  • Xiaoli Zhu, Hai Shi, Yalan Shen, Bin Zhang, Jing Zhao, Genxi Li. A green method of staining DNA in polyacrylamide gel electrophoresis based on fluorescent copper nanoclusters synthesized in situ. Nano Res., 2015, 8: 27142720


  • Ya Cao, Weiwei Chen, Peng Han, Zhuxin Wang, Genxi Li. Target-driven self-assembly of stacking deoxyribonucleic acids for highly sensitive assay of proteins. Anal. Chim. Acta, 2015, 890:16


  • Juan Zhang, Ying Liu, Xiaonan Wang, Yangyang Chen, Genxi Li. Electrochemical assay of α-glucosidase activity and the inhibitor screening in cell medium. Biosensors and Bioelectronics, 2015, 74: 666672


  • Juan Zhang, Jun Lv, Xiaonan Wang, Defeng Li, Zhaoxia Wang, Genxi Li. Integration of chemoselective ligation with enzyme specific catalysis: Saccharic colorimetric analysis using aminooxy/hydrazine-functionalized gold nanoparticles. Nano Res., 2015, 8(12):3853 3863


  • Xiaoli Zhu, Huihui Zhang, Chang Feng, Zonghuang Ye, Genxi Li. A dual-colorimetric signal strategy for DNA detection based on graphene and DNAzyme. RSC Adv.,2014, 4: 24212426


  • Xiaoying Wang, Hao Li, Xiaoxi Li, Yangyang Chen, Yongmei Yin, Genxi Li. Electrochemical assay of melanoma biomarker in human blood. Electrochem. Commun.,2014, 39: 1214


  • Juan Zhang, Lin Xiao, Yucai Yang, Zhaoxia Wang, Genxi Li. Lignin binding to pancreatic lipase and its influence on enzymatic activity. Food Chemistry, 2014, 149: 99106


  • Chao Li, Yucai Yang, Bin Zhang, Guifang Chen, Zhaoxia Wang, Genxi Li. Conjugation of graphene oxide with DNA modified gold nanoparticle to develop a novel colorimetric sensing platform. Part. Part. Syst. Charact., 2014, 31: 201208


  • Haona Xie, Hao Li, Yue Huang, Xiaoying Wang, Yongmei Yin, Genxi Li. Combining peptide and DNA for protein Assay: CRIP1 detection for breast cancer staging. ACS Applied Materials & Interfaces, 2014, 6: 459463


  • Tingting Yin, Hao Li, Nana Yang, Tao Gao, Lizhou Sun, Genxi Li. Detection of CREB phosphorylation via Zr (IV) ion mediated signal amplification. Biosensors and Bioelectronics, 2014, 56: 15


  • Ya Cao, Dehu Chen, Weiwei Chen, Jiacui Yu, Zhong Chen, Genxi Li. Aptamer-based homogenous protein detection using cucurbit[7]uril functionalized electrode. Anal. Chim. Acta, 2014, 812: 4549


  • Xiaoli Zhu, Chang Feng, Zonghuang Ye, Yangyang Chen, Genxi Li. Fabrication of magnetically controlled moveable architecture to develop reusable electrochemical biosensors. Scientific Reports, 2014, 4: 4169


  • Yue Yu, Tao Gao, Hao Li, Zonghuang Ye, Zhong Chen, Genxi Li. A novel electrochemical immunosensor for Golgi Protein 73 assay. Electrochem. Commun., 2014, 42: 68


  • Hao Li, Yue Huang, Bin Zhang, DaweiYang, Xiaoli Zhu, Genxi Li. A new method to assay protease based on amyloid misfolding: application to prostate cancer diagnosis using a panel of proteases biomarkers. Theranostics, 2014, 4: 701707


  • Limin Ning, Xiaoxi Li, Dawei Yang, Peng Miao, Zonghuang Ye, Genxi Li. Measurement of intracellular pH changes based on DNA-templated capsid protein nanotubes. Anal. Chem., 2014, 86: 80428047


  • Chao Li, Luming Wei, Xinjian Liu, Lin Lei, Genxi Li. Ultrasensitive detection of lead ion based on target induced assembly of DNAzyme modified gold nanoparticle and graphene oxide. Anal. Chim. Acta, 2014, 831: 6064


  • Yue Huang, Hao Li, Tao Gao, Xinjian Liu, Genxi Li. A sensitive method for protein assays using a peptide-based nano-label: human glypican-3 detection for hepatocellular carcinomas diagnosis. Analyst, 2014, 139: 37443747


  • Xiaoxi Li, Peng Miao, Limin Ning, Tao Gao, Zonghuang Ye, Genxi Li. Study of the interaction between graphene oxide and surface-confined biomolecules to develop new kind of biosensors. Curr. Nanosci., 2014, 10: 801806


  • Dianyuan Zheng, Zonghuang Ye, Shiya Yang, Yun Li, Xiaomei He, Genxi Li. An electrochemical method to evaluate p53 C-terminal domain acetylation on its DNA binding ability. Electrochem. Commun., 2014, 49: 3033


  • Juan Zhang, Junhui Cui, Ying Liu, Yangyang Chen, Genxi Li. A novel electrochemical method to determine α-Amylase activity. Analyst, 2014, 139: 34293433


  • Hongxia Chen, Jiangjiang Zhang, Xinjian Liu, Yanmin Gao, Zonghuang Ye, Genxi Li. Colorimetric copper (II) ion sensor based on the conformational change of peptide immobilized onto the surface of gold nanoparticles. Anal. Methods, 2014, 6: 25802585


  • Nana Yang, Hao Li, Tingting Yin, Yue Huang, Lizhou Sun, Genxi Li. A new method to assay hypoxia-inducible factor-1 based on small molecule binding DNA. Anal. Chim. Acta, 2014, 838: 3136


  • Yucai Yang, Chao Li, Li Yin, Muyun Liu, Zhaoxia Wang, Yongqian Shu, Genxi Li. Enhanced charge transfer by gold nanoparticle at DNA modified electrode and its application to label-free DNA detection. ACS Applied Materials & Interfaces, 2014, 6: 75797584


  • Hongxia Chen, Yafei Hou, Fangjie Qi, Jiangjiang Zhang, Kwangnak Koh, Zhongming Shen, Genxi Li. Detection of vascular endothelial growth factor based on rolling circle amplification as a means of signal enhancement in surface plasmon resonance. Biosensors and Bioelectronics, 2014, 61: 8387


  • Jing Zhao, Suisui Hu, Weidong Zhong, Jiguang Wu, Zhongming Shen, Zhong Chen, Genxi Li. Highly sensitive electrochemical aptasensor based on a ligase-assisted exonuclease III-catalyzed degradation reaction. ACS Applied Materials & Interfaces, 2014, 6: 70707075


  • Guifang Chen, Hui Tong, Tao Gao, Yangyang Chen, Genxi Li. Direct application of gold nanoparticles to one-pot electrochemical biosensors. Anal. Chim. Acta, 2014, 849: 16 (cover page)


  • Xiaoxi Li, Nana Yang, Yuanyuan Zhang, Hao Li, Tingting Yin, Lizhou Sun*, Genxi Li*. Sensitive detection of transcription factors Kaiso via self-assembly of DNA on an electrode surface. Electroanalysis, 2014, 26: 25202525


  • Tao Gao, Dawei Yang, Limin Ning, Lin Lei, Zonghuang Ye, Genxi Li. Ultrafine and well dispersed silver nanocrystals on 2D nanosheets: synthesis and application as a multifunctional material for electrochemical catalysis and biosensing. Nanoscale, 2014, 6: 1482814835


  • Hao Li, Yue Huang, Bin Zhang, Xiaoshu Pan, Xiaoli Zhu, Genxi Li. Method to study stoichiometry of protein post-translational modification. Anal. Chem., 2014, 86: 1213812142


  • Ya Cao and Genxi Li, “Engineering Aptamers for Biomedical Applications: Part I”, in “Engineering in Translational Medicine”, Edited by Weibo Cai, pp. 397-426, Springer-Verlag London, 2014.


  • Jing Zhao, Qi Fan, Sha Zhu, Aiping Duan, Yongmei Yin, Genxi Li. Ultra-sensitive detection of Ag+ ions based on Ag+-assisted isothermal exponential degradation reaction. Biosensors and Bioelectronics,2013, 39: 183186


  • Jing Zhao, Yalin Yan, Li Zhu, Xiaoxi Li, Genxi Li. An amperometric biosensor for the detection of hydrogen peroxide released from human breast cancer cells Biosensors and Bioelectronics,2013, 41: 815819


  • Xiaoli Zhu, Jinghua Yang, Min Liu, Yao Wu, Zhongmin Shen, Genxi Li. Sensitive detection of human breast cancer cells based on aptamer-cell-aptamer sandwich architecture. Anal. Chim. Acta, 2013, 764: 5963


  • Dehu Chen, Min Shen, Ya Cao, Bing Bo, Zhong Chen, Yongqian Shu, Genxi Li. Electrochemical identification of hepatocellular carcinoma based on the assay of human cervical cancer oncoprotein-1 in serum. Electrochem. Commun., 2013, 27: 3841


  • Ya Cao, Jiacui Yu, Bing Bo, Yongqian Shu, Genxi Li. A simple and general approach to assay protease activity with electrochemical technique. Biosensors and Bioelectronics, 2013, 45: 15


  • Dianyuan Zheng, Xuejun Zhu, Xiaorong Ding, Xiaoli Zhu, Yongmei Yin, Genxi Li. Sensitive detection of CD147/EMMPRIN and its expression on cancer cells with electrochemical technique. Talanta, 2013, 105: 187191


  • Hao Li, Haona Xie, Ya Cao, Xiaorong Ding, Yongmei Yin, Genxi Li. A general way to assay protein by coupling peptide with signal reporter via supermolecule formation. Anal. Chem., 2013, 85: 10471052


  • Dianyuan Zheng, Xiaoli Zhu, Xuejun Zhu, Bing Bo, Yongmei Yin, Genxi Li. An electrochemical biosensor for the direct detection of oxytetracycline in mouse blood serum and urine. The Analyst, 2013, 138: 18861890


  • Jing Zhao, Tao Gao, Yalin Yan, Guifang Chen, Genxi Li. Probing into the interaction of β-amyloid peptides with bilayer lipid membrane by electrochemical techniques . Electrochem. Comm., 2013, 30: 2628


  • Xiaoli Zhu, Liya Sun, Yangyang Chen, Zonghuang Ye, Genxi Li. Combination of cascade chemical reactions with graphene-DNA interaction to develop new strategy for biosensor fabrication. Biosensors and Bioelectronics, 2013, 47: 3237


  • Xiaorong Ding, Hao Li, Haona Xie, Yue Huang, Yafei Hou, Yongmei Yin, Genxi Li. A novel method to assay molecular chaperone activity of HSP70: evaluation of drug resistance in cancer treatment. Biosensors and Bioelectronics, 2013, 47: 7579


  • Chao Li, Zhaoyin Wang, Tao Gao, Aiping Duan, Genxi Li. Fabrication of hand-in-hand nanostructure for one-step protein detection. Chem. Commun., 2013, 49: 37603762


  • Bing Bo, Xuejun Zhu, Peng Miao, Dong Pei, Bo Jiang, Yue Lou, Yongqian Shu, Genxi Li. An electrochemical biosensor for clenbuterol detection and pharmacokinetics investigation. Talanta, 2013, 113: 3640


  • Aiping Duan, Limin Ning, Chao Li, Yafei Hou, Nana Yang, Lizhou Sun, Genxi Li. A novel strategy to inhibit the reproduction and translation of hepatitis C virus. Sci. China Life Sci.,2013, 56: 293297


  • Hao Li, Haona Xie, Nana Yang, Yue Huang, Lizhou Sun, Genxi Li. Design of a bi-functional peptide for protein assay: observation of cortactin expression in human placenta. Chem. Commun.,2013, 49: 53875389


  • Sha Zhu, Ya Cao, Yuanyuan Xu, Yongmei Yin, Genxi Li. An exonuclease III protection-based electrochemical method for estrogen receptor assay. Int. J. Mol. Sci., 2013, 14: 1029810306


  • Juan Zhang, Junhui Cui, Tingting Yin, Lizhou Sun, Genxi Li. Activated effect of lignin on alpha- Amylase. Food Chem., 2013, 141: 22292237


  • Tao Gao, Limin Ning, Chao Li, Haiyan Wang, Genxi Li. A colorimetric method for protein assay via exonuclease III-assisted signal attenuation strategy and specific DNA-protein interaction. Anal. Chim. Acta, 2013, 788: 171176


  • Limin Ning, Peng Miao, Tao Gao, Haiyan Wang, Genxi Li. Preparation and assembly of collagen-DNA complex on an electrode surface and its application for protein analysis . Electrochim. Acta, 2013, 111: 499503


  • Hao Li, Haona Xie, Yue Huang, Bing Bo, Xiaoli Zhu, Yongqian Shu, Genxi Li. Highly sensitive protein detection based on a novel probe with catalytic activity combined with a signal amplification strategy: assay of MDM2 for cancer staging. Chem. Commun., 2013, 49: 98489850


  • Jing Zhao, Li Zhu, Chao Guo, Tao Gao, Xiaoli Zhu, Genxi Li. A new electrochemical method for the detection of cancer cells based on small molecule-linked DNA . Biosensors and Bioelectronics, 2013, 49: 329333


  • Xiaoli Zhu, Min Liu, Huihui Zhang, Haiyan Wang, Genxi Li. A chemical approach to accurately characterize the coverage rate of gold nanoparticles. J. Nanopart. Res., 2013, 15: 19001907


  • Bing Bo, Peng Miao, Yuanyuan Xu, Yongqian Shu, Genxi Li. A novel method to investigate ribonuclease activity of Dicer by square wave voltammetry. Electrochem. Commun., 2013, 34: 142145


  • Hongxia Chen, Qiaohan Mei, Yafei Hou, Xiaoli Zhu, Kwangnak Koh, Xiaoxi Li, Genxi Li. Fabrication of a protease sensor for caspase-3 activity detection based on surface plasmon resonance. The Analyst, 2013, 138: 57575761

  • Limin Ning, Xiaoxi Li, Xiaorong Ding, Yongmei Yin, Genxi Li. An iRGD based strategy to study electrochemically the species inside a cell. Int. J. Mol. Sci., 2012, 13, 1042410431


  • Zhaoyin Wang, Limin Ning, Aiping Duan, Xiaoli Zhu, Haiyan Wang, Genxi Li.A set of logic gates fabricated with G-quadruplex assembled at an electrode surface. Chem. Commun., 2012, 48, 75077509


  • Jing Zhao, Li Zhu, Xiaoxi Li, Bing Bo, Yongqian Shu, Genxi Li.An electrochemical method to assay the reversal effect on multi-drug resistance in tumor cells. Electrochem. Commun.,2012, 23: 5658


  • Guifang Chen, Yangyang Chen, Nana Yang, Xuejun Zhu, Lizhou Sun, Genxi Li.Interaction between curcumin and mimetic biomembrane. Sci. China Life Sci.,2012, 55: 527532


  • Ya Cao, Sha Zhu, Jiacui Yu, Xuejun Zhu, Yongmei Yin, Genxi Li.Protein detection based on small molecule-linked DNA. Anal. Chem.,2012, 84: 43144320


  • Nana Yang, Ya Cao, Ping Han, Xuejun Zhu, Lizhou Sun, Genxi Li.Tools for investigation of the RNA endonuclease activity of mammalian argonaute2 protein. Anal. Chem., 2012, 84: 24922497


  • Hao Li, Ya Cao, Xiaolan Wu, Zonghuang Ye, Genxi Li.Peptide-based electrochemical biosensor for amyloid ß 1-42 soluble oligomer assay. Talanta, 2012, 93: 358363


  • Min Shen, Mei Yang, Hao Li, Zhiqiang Liang, Genxi Li. A novel electrochemical approach for nuclear factor kappa B detection based on triplex DNA and gold nanoparticles. Electrochim. Acta, 2012, 60: 309313


  • Peng Miao, Limin Ning, Xiaoxi Li, Pengfei Li, Genxi Li.Electrochemical strategy for sensing protein phosphorylation. Bioconj. Chem., 2012, 23: 141145


  • Qi Fan, Jing Zhao, Hao Li, Li Zhu, Genxi Li. Exonuclease III-based and gold nanoparticle-assisted DNA detection with dual signal amplification. Biosensors and Bioelectronics, 2012, 33: 211215


  • Jing Zhao, Xiaolin He, Bing Bo, Xinjian Liu, Yongmei Yin, Genxi Li.A “signal-on” electrochemical aptasensor for simultaneous detection of two tumor markers. Biosensors and Bioelectronics, 2012, 34: 249252


  • Jing Zhao, Xiaolin He, Nana Yang, Lizhou Sun, Genxi Li.Study of drug metabolism by xanthine oxidase. Int. J. Mol. Sci. , 2012, 13: 48734879


  • Jing Wang and Genxi Li, “Colorimetric Multiplexed Immunoassay for Sequential Detection of Tumor Markers”, in “Biosensors and Molecular Technologies for Cancer Diagnostics”, Edited by Keith E. Herold and Avraham Rasooly, pp. 441-453, CRC Press, Taylor & Francis Group, Boca Raton, Florida, USA, 2012.


  • Genxi Li and Peng Miao, “Electrochemical Analysis of Proteins and Cells”, Springer, Berlin, Germany, 2012.


  • Qianlu Yang, Jing Zhao, Nandi Zhou, Zonghuang Ye, Genxi Li. Electroanalysis of telomere-bending motions caused by hTRF1. Biosensors and Bioelectronics,2011, 26: 22282231


  • Jinghua Yang, Jiang Zhao, Han Xiao, Dongmei Zhang, Genxi Li. Study of hemoglobin and
    human serum albumin glycation with electrochemical techniques. Electroanalysis, 2011, 23: 463468


  • Jing Wang, Ya Cao, Yun Li, Zhiqiang Liang, Genxi Li. Electrochemical strategy for detection
    of phosphorylation based on enzyme-linked electrocatalysis.
    J. Electroanal. Chem., 2011, 656: 274


  • Zhaoyin Wang, Lei Liu, Yuanyuan Xu, Lizhou Sun, Genxi Li. Simulation and assay of protein biotinylation with electrochemical technique. Biosensors and Bioelectronics, 2011, 26:


  • Yuanyuan Xu, Jing Wang, Ya Cao, Genxi Li.Gold nanoparticles based colorimetric assay of protein poly(ADP-ribosyl)ation. Analyst, 2011, 136: 20442046


  • Jing Zhao, Tao Liu, Qi Fan, Genxi Li.
    A new strategy for a DNA assay based on a target-triggered isothermal exponential degradation reaction.
    Chem. Commun., 2011, 47: 5262


  • Min Shen, Jing Wang, Mei Yang, Genxi Li.
    Direct electrochemistry of the Ti(IV)-transferrin complex: Probing into the transport of Ti(IV) by human serum transferrin .
    Electrochem. Commun., 2011, 13: 114


  • Jing Zhao, Guifang Chen, Li Zhu, Genxi Li.Graphene quantum dots-based platform for the fabrication of electrochemical biosensors. Electrochem. Commun., 2011, 13: 3133


  • Xiaoli Zhu, Jing Zhao, Yao Wu, Zhongming Shen, Genxi Li.Fabrication of a highly sensitive aptasensor for potassium with a nicking endonuclease-assisted signal amplification strategy. Anal. Chem., 2011, 83: 40854089


  • Jing Wang, Genxi Li.Aptamers against cell surface receptors: selection, modification and application. Curr. Med. Chem., 2011, 18:41074116


  • Peng Miao, Limin Ning, Xiaoxi Li, Yongqian Shu, Genxi Li. An electrochemical alkaline phosphatase biosensor fabricated with two DNA probes coupled with λ exonuclease. Biosensors and Bioelectronics, 2011, 27: 178182




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